Application of Probiotics for New Products

Application of Probiotics for New Products


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Other Animal Feeds

Mediogen Co., Ltd.

Country / Year Established
South Korea South Korea /
Business type
Others
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16

DUNS

Product name Application of Probiotics for New Products Certification -
Category Other Animal Feeds Ingredients -
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origin Stock -
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Product Information

Ginseng Tea using Spore-forming Lactic Acid Bacteria

  1. Main function of Bacillus coagulans MG520
    It is spore-forming lactic acid bacteria which germinate rapidly in the intestinal tract and proliferate for a long time. It converts sugars to lactic acid. This acid can inhibit the growth of bacteria such as Listeria, Salmonella, Pseudomonas, etc. which can cause illness. This microorganism proved effective in lowering LDL cholesterol.
  2. Physiological property of Bacillus coagulans MG520
    • Durability : Its storage stability is about 90% for 12 months at room temperature.
    • Heat resistance : Bacillus coagulans MG520 spores survive above 70% after incubation for 20 minutes in hot water(80°C).
    • Acid tolerance : The survival rate of microorganism is over 90%(pH 4.0, 1hrs)
  3. Synergy effect Ingestion of both Lactic acid bacteria and Ginseng
    Lactic acid bacteria play an important role in maintaining the desirable balance of normal microflora in the human digestive system. Also Ginseng has multiple function and effects on the human body. So Ginseng Tea containing spore forming Lactic acid bacteria provides synergy effects.

Survival rate of Bacillus coagulans MG520 as time passes after treated with hot water(80°C)

Lactic acid bacteria for the alcohol metabolism and liver function

Alcohol consumption has numerous health consequences for the human body. L. fermentum MG590 isolated in our laboratory produce alcohol dehydrogenase and acetaldehyde dehydrogenase. In particular, L. fermentum protects the liver from alcohol metabolism enhances specific liver functions.

Effect of L. fermentum MG590 addition on BAC after oral administration.
Alc only: 1 ml unsed medium + 2 ml 22% alcohol drink,
L. fermentum + Alc: 1 ml L. fermentum MG590 + 2 ml 22% alcohol drink.

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GOT and GPT activities in vivo test with SD rats fed with L. fermentum MG590 and/or 22% alcohol drink.
The SD rats were fed with different supplements: feeding 3 ml water (Control), 1 ml L. fermentum MG590 containing 2 ml of 22% alcohol (L. fermentum + Alc) and 3 ml of 22% alcohol only (Alc only). The GOT and GPT were measured before (A) and 2 hr (B) after oral administration of the supplements.

Fermented herb

Fermented CA for the allergy treatment

Probiotics have been previously proven effective in allergic inflammation and food allergy. Probiotics also enhance gut specific IgA responses, which are often defective in children with food allergy. They also help to promote gut barrier function and restore normal gut microbiology, alterations in which have been shown in allergic individual.

Inhibitory effect of herb CA fermented by lactic acid bacteria on IgE production in mouse
Fermented herb CA powder administered with oral for 6 days before treatment of compound 48/80. The blood from mice collected at 1h after treatment of compound 48/80. The content of IgE in blood was measured.

Inhibitory effect of herb CA fermented by lactic acid bacteria on eosinophil number in mouse
Fermented herb CA powder administered with oral for 6 days before treatment of compound 48/80. The blood from mice collected at 1h after treatment of compound 48/80. The content of eosinophil(number/mm3) in blood was measured.

Fermented ginseng

The American Society for Pharmacology and Experimental Therapeutics vol. 31, No.8 1091/1082381
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Fermented ocher

Free radical eliminating activity by fermented ocher

1. supernatant of ocher
2. broth fermented by L. bulgaricus broth fermented by L. bulgaricus with 50% ocher
3. broth fermented by L. acidophilus broth fermented by L. acidophilus with 50% ocher
4. broth fermented by L. plantarum broth fermented by L. plantarum with 50% ocher
5. broth fermented by L. rhamnosus broth fermented by L. rhamnosus with 50% ocher
6. broth fermented by St. thermophilus broth fermented by St. thermophilus with 50% ocher
7. broth fermented by Bi. longum broth fermented by Bi. longum with 50% ocher

Free radical eliminating activity by fermented ocher

1. supernatant of ocher
2. broth fermented by L. bulgaricus broth fermented by L. bulgaricus with 30% ocher
3. broth fermented by L. acidophilus broth fermented by L. acidophilus with 30% ocher
4. broth fermented by L. plantarum broth fermented by L. plantarum with 30% ocher
5. broth fermented by L. rhamnosus broth fermented by L. rhamnosus with 30% ocher
6. broth fermented by St. thermophilus broth fermented by St. thermophilus with 30% ocher
7. broth fermented by Bi. longum broth fermented by Bi. longum with 30% ocher

Probiotics contained with organic selenium

B2B Trade

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Mediogen Co., Ltd.

Country / Year Established
South Korea South Korea /
Business type
Others

16

DUNS

President
Nam-Soo, Paek
Address
#1504, Masterstower, 553, Mapo-gu, Seoul, Korea
Product Category
Herbal Medicine,Other Animal Feeds
No. of Total Employees
1-50
Company introduction

MEDIOGEN Co., Ltd. was established in 2000.
MEDIOGEN Co., Ltd. is a bioventure corporation based on the microbial biotechnology, and life science. We have focused on the research, development and production of the highest quality probiotics for commercial applications such as health food, dairy products and herb fermentation. Particularly MEDIOGEN produces characteristic probiotics for health food, aquaculture and domestic animal. In addition, we research and develop multifunctional food materials, functional feedstuffs. So our products have high survival rate in long storage, acid tolerance and bile acid resistance.

2000.  06.  MEDIOGEN Corporation was founded
2000.  07. Manufacturing of initial products
2000.  12. Registration of Food manufacture and marketing
2001.  02. Acknowledged as an excellent venture enterprise by the Small and Medium Business Administration
2001.  05. Moving in paju at GyeonggiDo
2001.  11. Registration of Feed additives manufacture
2005.  06. Acknowledged as an excellent technique enterprise by the KIBO
2006.  07. Acknowledged as an INNOBIZ enterprise by the Small and Medium Business Administration
2007.  05. Moving in Jecheon at Chungcheongbuk-Do
2007.  11. Certification of ISO 9001:2000 by MSA

Probiotics products of MEDIOGEN
Strain 
Lactobacillas brevis MG19
Lactobacillas plantarum MG208
Lactobacillas acidophilus MG501
Lactobacillas rhamnosus MG315
Lactobacillas casei MG311
Lactobacillas reuteri MG505
Lactobacillas bulgaricus MG515
Lactobacillas fermentum MG590
Lactococcus lactis MG530 Enterococcus faecium MG89

Streptococcus thermophilus MG510
Bifidobacterium longum MG723
Bifidobacterium infantis MG727
Bifidobacterium breve MG729
Bifidobacterium bifidum MG720
Bacillus coagulans MG520
Bacillus subtilis MG401
Bacillus natto MG410
Bacillus polyfermenticus MG440

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