HA is the main component composing human intercellular substance, vitreum joints synovia, etc. It can retain water, keep intercellular space, accommodate osmotic pressure, lubricate and further rehabilitation of cells. In its aqueous solution, a mount of carboxyl and hydroxy in its molecular, which can form hydrogen bondings in molecule and between molecules, thus making it a powerful water keeping action. It can bond water over 400 multiple. In upper consistence, HA aqueous solution has high viscoelasticity because of its molecules form complex three reticula grades. As a main component of intercellular substance, HA directly concerns the transfer of exchange of electrolyte inside and outside cells, demonstrates the filter action of physical and molecule information. Macromolecule HA can prevent cells from move, hyperplasia, disintegration and engulfment, while low olecule HA has furtherance actions.
HA has peculiar physical and chemical property and biologic action, widely used in medicine. It can be used as a viscoelastic agent in artificial crystal planting in ocular surgery, as a fill agent in osteoarthritis, also as an agent in eye drops. It has good action of adhesion preventives in surgerical operations and healing cuts on skin. Compound of HA and other drug, the additive can make the action of drug delaying. With the development of medical technology. HA will be more widely used in medicine