PDT, acne cure using topical photodynamic therapy, actively treatmented on the center of local and overseas new hospital but, that effect and safe concerned, there is basic dispute. existing ALA hydrophilicity property substance, it take downtime to get through the cell, and accompany the Efficiency especially, acne photodynamic therapy targeted mainly sebaceous glands, due to ALA hydrophilicity property Problem, there is the difficulty of absorption and excretion and because of it, there is side effect of PIH and tanning, burn etc.

BR PDT VIT.B2 (Riboflavin =amino acid),as pro -fat solubility fast absorption, excreted as protein metabolite fraction process no side effect and safe topical photodynamic therapy acne treatment. with BR itself technology applied and patented vitamin B2=Amino acid topical photodynamic therapy university hospital clinical demonstration and thesis announcement and clinical application test announcement etc of new hospital, actually clinical related data secured and certified products.