Anti-CD22 (hLL2)-SN-38 ADC

Anti-CD22 (hLL2)-SN-38 ADC


Negotiable Min Order Quantity Unit

Required Quantity
Place of Origin
U.S.A
Payment Terms
Negotiable
Production method
Negotiable
Shipping / Lead Time
Negotiable / Negotiable
Keyword
adc
Category
Pharmaceuticals

Creative Biolabs

Membership
BIZ
Country / Year Established
U.S.A U.S.A / 2005
Business type
Manufacturer
Verified Certificate

8

DUNS

Product name Anti-CD22 (hLL2)-SN-38 ADC Certification -
Category Pharmaceuticals Ingredients -
Keyword adc Unit Size -
Brand name - Unit Weigh -
origin U.S.A Stock -
Supply type - HS code -

Product Information

 

This ADC product is comprised of an anti-CD22 monoclonal antibody conjugated (clone hLL2) via a linker to SN-38. The SN-38  is targeted to certain cancers by immunerecognition and delivered into cancer cells via receptor mediated endocytosis. Within the cell, SN-38 binds to DNA, causes DNA damage. SN38 (7-ethyl-10-hydroxy camptothecin) is an active metabolite of the cancer prodrug, irinotecan, with the ability of inhibiting Topoisomerase I, which is belong to the camptothecin family. SN-38 is formed via hydrolysis of irinotecan by carboxylesterases and metabolized via glucuronidation by UGT1A1. 

 

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Price (FOB) Negotiable transportation -
MOQ Negotiable Leadtime Negotiable
Payment Options Negotiable Shipping time Negotiable

Creative Biolabs

Country / Year Established
U.S.A U.S.A / 2005
Membership
BIZ
Business type
Manufacturer

8

DUNS

President
Mr
Address
SUITE 203, 17 Ramsey Road, Shirley, NY 11967, USA
Product Category
Other Pharmaceutical Chemicals
Year Established
2005
Company introduction

 

Creative Biolabs is a leading company of recombinant antibody (rAb) discovery and manufacturing, providing high quality service to customers in academia and industry fields all over the world.
 
Our cutting-edge hybridoma development and phage display platforms allow the production of the most comprehensive list of recombinant antibody products and extensive service portfolio at the most competitive price. Our products range from antibody / peptide libraries, Biosimilar cell lines, Chimeric antigen receptor (CAR) products, antibody-drug conjugates (ADCs) to engineered antibodies such as therapeutic antibodies, nanobodies, bispecific antibodies and intrabodies. We also provide professional custom antibody discovery and engineering services, featuring phage display library construction, antibody humanization, chimerization, engineered antibody production (Fab, scFc, tribody, bispecific antibody, nanobody, minibody, etc.), antibody labeling, hybridoma/stable cell line development, membrane protein production and cGMP-manufacturing which enable larger scale antibody production for development of animal-based assays and clinical trials.

 

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