Manufacturer BioScience GmbH placed the injectable dermal filler Hyacorp (types H1000 and H-S) on the Dutch market through its distributors. These are fillers that are not only applied medically but for cosmetic purposes as well. When injected into the face, these fillers enhance the volume of the injected facial area, tightening the skin. Fillers usually have a temporary effect. To sustain the desired result, patients should undergo regular filler treatments. The chemical composition of the Hyacorp product is such that the result allegedly outlasted that of other fillers, and repeat treatment could be postponed. However, over time it became apparent that it was not possible or very difficult for the body to break down the injected Hyacorp. Thus the fillers displayed traits of permanent fillers that are not at all intended for use in the facial area.