Mutant Library Construction Service
Negotiable Min Order Quantity Unit
- Required Quantity
-
- Place of Origin
- U.S.A
- Brand name
- CD Genomics
- Payment Terms
- Negotiable
- Production method
- Negotiable
- Shipping / Lead Time
- Negotiable / Negotiable
- Keyword
- protein, dna sequencing, mutant, novo gene
- Category
- Pharmaceutical Intermediates
CD Genomics
U.S.A
- Verified Certificate
-
10
| Product name | Mutant Library Construction Service | Certification | - |
|---|---|---|---|
| Category | Pharmaceutical Intermediates | Ingredients | - |
| Keyword | protein , dna sequencing , mutant , novo gene | Unit Size | - |
| Brand name | CD Genomics | Unit Weigh | - |
| origin | U.S.A | Stock | - |
| Supply type | - | HS code | - |
Product Information
In vitro molecular optimization is a very efficient means of generating mutant proteins with improved or novel properties, identifying regulatory sequences, and probing for structurally and functionally critical residues. Mutant libraries constructed using the in vitro molecular optimization method provide one useful approach to the systematic study of protein properties, regulation, and function.
Our mutant library service includes:
1. Site-directed mutagenesis libraries
CD Genomics combines its expertise in de novo gene synthesis and site-directed mutagenesis into an excellent site-directed mutagenesis library construction service. The site-directed mutagenesis library offers a great platform for protein function and active center studies. In these libraries, any given residue can be substituted with any of other 19 common amino acids, creating systematic combinations of amino acid mutations that reveal any significant pattern.
2. Scanning point mutation libraries
Scanning point mutation is a systematic means of improving protein performance. It outperforms standard alanine/cysteine scanning by replacing each amino acid with all 20 amino acids simultaneously. This technique provides a detailed profile of each amino acid at the position. For each codon of interest, a small, site-saturated library is constructed. This library can be delivered as a pool or in a separated format for any substitution variant (19 in total). The application of CD Genomics's expertise in de novo gene synthesis to the field of sequential permutation scanning allows us to provide superb sequential permutation scanning library construction services.
3. Randomized and degenerated libraries
With our advanced degenerated oligonucleotide techniques, CD Genomics can generate any form of randomization or degeneration of full-length gene in a synthetic DNA fragment. This permits controlled, highly precise randomization within oligonucleotides. CD Genomics's in vitro library synthesis technology can introduce random substitutions on a controlled level with maximum flexibility. The mutation frequency can be set to any value between 1 and 20 mutations per kb. A peer group of 48, 96, or 192 individual transformants is sequence-verified.
B2B Trade
| Price (FOB) | Negotiable | transportation | - |
|---|---|---|---|
| MOQ | Negotiable | Leadtime | Negotiable |
| Payment Options | Negotiable | Shipping time | Negotiable |
- President
- Mr. Zhang
- Address
- 45-1 Ramsey Road, Shirley, NY 11967,USA
- Product Category
- Petrochemical Products
- No. of Total Employees
- 101-500
- Company introduction
-
We are aiming at providing the research community with high quality manual DNA sequencing services. Due to the demand for our services has increased, CD Genomics has already updated its technology platform to automated ABI instruments. At present, our senior bioinformaticians have ever viewed more than ten thousands of trace files and accumulated abundant experience with our 3730 and 3730XL analyzers. We continue to work hard to offer you the same dependable services to pharmaceutical and biotech companies, as well as academia and government agencies for the purpose of satisfying all your sequencing needs.
In 2007, CD Genomics has expanded its services to molecular biology research and its development needs. we have become a service provider in genotyping，library construction，and mutagenesis analyses. Our progress can not be achieved without our large group of client's support.
Through nearly ten year's hard working and depend on our professional work team, we are proud of satisfying the needs of our clients both at home and abroad, which across more than 50 countries and districts. We always devote ourselves to providing you with the best and professional service.
- Main Product
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